Dr. Ostrem has expertise in Maternal-Fetal and Pediatric Neurology and treats babies, children, young adults, and pregnant patients with neurological symptoms and disorders. She completed her M.D. and Ph.D. at UCSF followed by residency in Pediatric Neurology in the Mass General Brigham (Partners Neurology) Program in Boston, Massachusetts, and clinical fellowship in Maternal-Fetal Neurology at Brigham and Women's Hospital. She also completed a postdoctoral fellowship in the laboratory of Dr. Paola Arlotta at Harvard.
The Ostrem lab is focused on developing and improving treatments for neurological conditions of childhood. We are particularly interested in disorders affecting the white matter: the part of the nervous system involved in connecting different parts of the brain to one another and to the rest of the body. We are working on newborn brain disorders, such as white matter injury of prematurity, which can cause developmental delays, disability, cerebral palsy, seizures, and many other problems. We are also working on inflammatory and genetic conditions that affect white matter in patients of all ages. Dr. Ostrem is the UCSF site P.I. for a Phase 3, industry-sponsored clinical trial investigating a possible therapy for Angelman Syndrome.